­
­
­
­

Inventi Impact: Med Chem

Articles

  • Inventi:pmc/21154/16
    Antifungal and Antibacterial Activities of Phenyl and Ortho-\nHydroxy Phenyl Linked Imidazolyl Triazolo Hydroxamic Acid\nDerivatives
    15-Apr-2017 Research 2017 : April - June
    Supriyo Saha, Dilipkumar Pal*, Sushil Kumar

    Synthesized molecules (FP1-FP12) were evaluated against five fungal species as Candida albicans, Candida glabrata,\nCandida paropsialis, Candida tropicalis SSKM, Aspergillus niger using fluconazole as standard. Synthesized molecules (FP1-FP12)\nwere evaluated against five Gram +ve and five Gram -ve bacetria such as Bacillus cereus (+ve), Staphaylococcus saprophyticus\n(+ve), Streptococcus gordoni (+ve), Bacillus subtilis (+ve), Staphylococcus aureus (+ve) and Escherichia coli (-ve), Salmonella\ntyphimurium (-ve), Salmonella enterica (-ve), Proteus mirabilis (-ve), Pseudomonas aeruginosa (-ve) using tetracycline as standard.\nFP4 and FP10 were susceptible towards Candida albicans and Candida glabrata respectively. Except FP4 and FP10, all the\nmolecules showed dose dependent susceptible criteria against fungi. Among the synthesized molecules, FP6 was the best\nmolecule against gram +ve bacteria Bacillus subtilis, Staphylococcus aureus. FP10 was the best molecule against gram -ve\nbacteria Escherichia coli, Salmonella enterica.

    How to Cite this Article
    Supriyo Saha, Dilipkumar Pal, Sushil\nKumar. Antifungal and Antibacterial Activities of Phenyl\nand Ortho-Hydroxy Phenyl Linked Imidazolyl Triazolo\nHydroxamic Acid Derivatives. Inventi Impact: Med Chem,\n2017(2):42-49, 2017.
    Download Full Text